Electronic take-off is the way to go. Two large screens and a PDF mark-up program and you will never go back to paper print take-offs.
Just because I'm a bit old school, though, I do sometimes print out the plans on an 11 x 17 printer as well. It's cheap, and it helps me find what pages things are on quicker when I have to reference the architectural or plumbing/mechanical plans.
I actually do own a plotter, but I never print the plans out until it is a job I have under contract about to start. That's also a little way I have to make sure I never mix up bid prints with the permit prints.