The answer if it's a main breaker is no. If it's a branch circuit breaker, yes.
But, I suspect you really meant to ask something else. There are 225 AMP rated resi panels with 225 AMP busses and main breakers and I suspect this is what you saw.
But, I suspect you really meant to ask something else. There are 225 AMP rated resi panels with 225 AMP busses and main breakers and I suspect this is what you saw.